2011 Program

AGENDA AT-A-GLANCE  MMPE
December 5, 2011
10am – noon Registration at University of Colorado
Health Sciences Library
Reading Room, 3rd Floor
11:30 – 12:20 Lunch
12:00 – 12:10 Conference details
12:10 – 12:20 Welcome – David Pollock
12:20 – 1:00 Wright Keynote: Alfaro, A site-independent structurally constrained phylogenetic model of protein evolution
1:00 – 1:20 Kamneva: Modeling distribution of insertion/deletion length and probability using a mixture-modeling approach
1:20 – 2:00 Ohta Keynote: Liberles, The Devil’s advocate: What if Hill-Robertson effects account most strongly For non-Markovian sequence evolution?
2:00 – 2:20 Zacher:  Analysis of protein evolution with structure based measures
2:20 – 2:40 Afternoon Break
2:40 – 3:20 Zuckerkandl Keynote: de Koning, Bayesian analysis of context-dependent evolution in proteins
3:20 – 3:40 Safi:  Spontaneous appearance of drug resistance is one of the major practical implications of protein evolution
3:40 – 4:00 Loughran:  Functional consequence of positive selection revealed through rational mutagenesis of human myeloperoxidase
4:00 – 4:20 Teufel:  Towards a general model for duplicate gene retention and loss
4:20 – 5:00 Discussion on modeling mechanisms of protein evolution (led by Liberles, following Nescent paper and discussions)
6:30 – 8:30 Social Hour at the Rennaisance
8:30 – onwards Loosely organized dinner at local restaurants
December 6, 2011
8:30 – 9:00am Breakfast
9:00 – 9:40 Haldane Keynote: Pisani, Understanding Opsin evolution in non-bilaterian metazoans clarify the origin and early evolution of vision
9:40 – 10:00 Akanni:  Developing maximum likelihood and Bayesian supertrees
10:00 – 10:20 Koestler:  REvolver: Modeling sequence evolution under domain constraints
10:20 – 10:40 Morning Break
10:40 – 11:20 Mayr Keynote: McInerney, Goods-thinking versus tree-thinking: finding a place for all evolving entities
11:20 -11:40 Hamilton:  Diversification of visual receptors (opsin) coincides with major environmental factors such as the Cambrian explosion and the oxygenation of the oceans
11:40 – 12:00 Roger:   FunDi, a new tool for detecting functionally divergent sites in protein evolution
12:00 – 1:20pm Lunch Break
1:20 – 2:00 Dobzhansky Keynote: Chang, Molecular evolution of vertebrate visual pigments
2:00 – 2:20 Gutenkunst:  Protein domains with greater influence on network dynamics evolve more slowly
2:20 – 2:40 Castoe:  Convergence, coevolution, adaptation and systems biology
2:40 -3:00 Afternoon Break
3:00 – 3:40 A.C. Wilson Keynote: Pollock, Developing an integrative view of molecular coevolution, convergence, and adaptation
3:40 – 4:00 Doherty:  Gene duplicability in the mammalian protein-protein interaction network
4:00 – 4:20 Morgan:  Inferring the mammalian phylogeny using heterogeneous approach
4:20 – 5:00 Discussion on interaction of protein evolution and phylogenetic inference (led by Pollock)
5:00 – 5:10 Walk to campus pub
5:10 – 6:00 Continue discussion at campus pub
7:00 – onwards Loosely organized dinner at local restaurants
December 7, 2011
8:30 – 9:00am Breakfast
9:00 – 9:40 Kimura Keynote: Yokoyama, Convergence, coevolution, and adaptive evolution of transcription factors
9:40 -10:00 O’Connell:  The origin of mammalian placentation correlates with protein functional shift and the emergence of new control mechanisms
10:00 -10:20 Hermansen:  The Adaptive Evolution Database: an improved tool for detecting positive selection
10:20 – 10:40 Morning Break
10:40 – 11:20 Fisher Keynote: Masel Molecular errors, cryptic sequences, and evolvability of proteins
11:20 – 11:40 Haggerty:  A network-based approach to finding fusion genes
11:40 -11:50 Closing Remarks – Pollock